Advantage Spot-On 80mg

Each 0.8 ml single-dose pipette contains 80 mg of imidacloprid.

Declared excipients include benzyl alcohol, butylhydroxytoluene and propylene carbonate.

Advantage 80 mg is intended for cats and pet rabbits weighing 4 kg or more.

For animals weighing less than 4 kg, use the appropriate Advantage presentation for their body weight.

New fleas emerging in the environment may continue to cause re-infestation for six weeks or longer. Treat the home environment and other animals when appropriate.

Dosage: use one complete 0.8 ml pipette for each cat or pet rabbit weighing 4 kg or more.

Opening: hold the pipette upright, twist and pull off the cap, then use the reversed cap to break and remove the seal.

Application: part the hair on the neck at the base of the skull until the skin is visible.

Delivery: place the pipette tip directly on the skin and squeeze firmly several times until it is completely empty.

Important: apply only to undamaged skin and do not allow recently treated animals to groom one another.

Imidacloprid is an ectoparasiticide belonging to the chloronicotinyl group of compounds.

It binds to nicotinic acetylcholine receptors in the insect nervous system, causing interruption of nerve transmission, paralysis and death of the flea.

After topical application, the solution is rapidly distributed over the animal’s skin and coat. Systemic absorption is very low and is not relevant to the clinical efficacy of the product.

In addition to its activity against adult fleas, imidacloprid also acts against flea larvae in the surroundings of a treated animal.

Do not use in unweaned kittens younger than 8 weeks.

Do not use in pet rabbits younger than 10 weeks.

Do not use in cases of hypersensitivity to imidacloprid or any excipient.

This product is for topical use only and must not be administered orally.

Avoid contact with the animal’s eyes and mouth. Remove any collar before application and replace it only when the treated area is dry.

Do not use in rabbits intended for human consumption.

People with known hypersensitivity to imidacloprid should avoid contact with the product.

Avoid contact with the skin, eyes and mouth. Do not massage the application site.

Do not eat, drink or smoke during application. Wash hands thoroughly after use.

If the product enters the eyes, rinse thoroughly with water. If irritation persists or the product is swallowed, seek medical advice and show the package leaflet or label.

Do not stroke or groom treated animals until the application site is dry, usually within approximately one hour.

The solvent may stain leather, fabrics, plastics and finished surfaces. Allow the treated area to dry before contact with these materials.

Very rare: agitation; diarrhoea, hypersalivation or vomiting; neurological disorders such as depression, incoordination or tremor; and application-site reactions such as hair loss, itching, reddening or skin lesions.

Hypersalivation may occur if the animal licks the application site immediately after treatment because of the bitter taste. It normally disappears within a few minutes without treatment.

In rare cases of overdose or licking of treated fur, neurological signs may occur. Seek veterinary advice if signs develop, persist or worsen.

Pregnancy and lactation: available evidence suggests that adverse effects are not expected, although studies in pregnant and lactating queens and does are limited.

Interactions: no incompatibility has been observed with lufenuron, pyrantel, praziquantel or routine treatments including vaccination.

Water: the product remains effective if the animal becomes wet, although re-treatment may be necessary depending on environmental flea pressure. Do not repeat more often than once weekly.

Storage: no special storage conditions are required. Keep the pipettes in their original packaging until use and out of the reach of children.

Disposal: dispose of used pipettes immediately. Do not release unused product into the environment and follow local rules for veterinary medicines.